The ZEUS Black-Box is an integrated verification and traceability platform designed to eliminate human error and sample mix-ups during embryo biopsy and other IVF manipulations performed under a stereomicroscope. It uses a multi-layered sensor signaling system to monitor procedures and In the event of a deviation, the system issues an immediate alert and suspends the procedure, resuming only once the error is rectified in real time.

The system has two modules: The BioPSafe Module (for embryo biopsy verification and PCR tube matching) and the Multi-Purpose Module (for managing routine IVF manipulations and dish-to-dish transfers)

The system operates on three integrated control layers: Positional Verification: Sensors monitor the exact position of dishes and droplets. Sequence Control: Transfers must follow a predefined sequence via interface set by the embryologist. Digital Documentation: Every action is recorded with video, timestamps, and operator identity. If any deviation occurs, the system triggers an alert and automatically halts the process until corrected

While conventional systems confirm the identity between the patient and the petri dish, they often do not track individual embryos inside the dish. ZEUS BioPSafe ensures the right embryo reaches the right patient by verifying the link between a specific embryo and its designated PCR tube.

The system continuously monitors source and target locations using infrared distance sensors. If any deviation from the predefined sequence or a positional mismatch is detected, the system immediately alerts the user, automatically halts the process, and only allows continuation once the error is corrected.

It utilizes multiple integrated infrared sensors that detect the exact position of dishes, lanes, and droplets. If any mismatch or positional deviation occurs during a transfer step, the system immediately alerts the user and halts the procedure until corrected.

Embryologists use a Bluetooth-connected Conformation Foot Pedal. Pressing the right pedal logs a "Pick-Up" (aspiration) action, and pressing the left pedal logs a "Drop" (dispensing) action in the software

The system generates a complete audit trail by recording all Pick-Up and Drop actions. This includes synchronized video recordings, timestamps, and operator identity captured via the tablet's front camera.

It is an integrated set of tools designed to improve safety, traceability, and efficiency during the freezing and thawing process, and quadruple (4X) the storage capacity of the Nitrogen tanks.

The system utilizes ZEUS Smart Straws, which feature a patented unique shortenable design that can be broken at a designated point after freezing. This, combined with the triangular design and octagonal goblet system, can quadruple (4X) the storage capacity of existing liquid nitrogen tanks.

The goblet is designed with a nitrogen-retaining structure that allows liquid nitrogen to remain inside when removed from the tank, preventing air exposure. Its octagonal shape ensures that straw tips containing embryos or oocytes are continuously submerged during handling and scanning

The system ensures embryos never contact air during handling, maintaining a continuous cryogenic chain. The octagonal goblet is placed within the ZEUS Aluminum-Block inside the ZEUS Cryo-Box, allowing straw tips to remain safely submerged in liquid nitrogen while barcodes are scanned with a wireless reader. Once verified, the shortened straws are safely retrieved using a precision grabber pen, which maintains appropriate protection to the sample's integrity throughout the thawing process.

Yes, the system uses specially designed, liquid nitrogen-resistant barcodes. These labels are durable, remaining readable even while submerged in nitrogen to ensure long-term traceability.

The system utilizes dedicated software to record all data from the initial stages of the freezing and thawing process. A mobile barcode reader next to the Nitrogen tank then confirms the embryo’s identity at every subsequent step. This ensures an exact match between the cryopreserved or thawed embryo and the corresponding PGT report, verifying the correct sample identity prior to thawing.

The system uses a Touch-Screen Tablet running dedicated ZEUS software paired with liquid nitrogen-resistant barcode labels and a mobile barcode readerThis integration provides full in-tank addressing and library location indexing, enabling the system to track the exact tank, canister, cane, goblet, and straw location of every sample. Consequently, for thawing process users can pinpoint and verify sample locations in real time without the need to remove them from the nitrogen.

It is an electroporation system that delivers precisely regulated electrical pulses to create reversible pores in the oocyte membrane. This triggers physiological-like calcium signaling necessary for fertilization.

The system includes the touchscreen stimulator unit, sterile Electroliquid Solution powder, a U-shaped metal Dish Fastener for thermal stability under the microscope, and single-use Electro Dishes with integrated metal electrodes.

The device is indicated for cases where natural or ICSI-induced calcium oscillations are insufficient, including Total Fertilization Failure (TFF), low fertilization rates (<30%), severe male factor infertility (globozoospermia), Round Spermatid Injection (ROSI), and totally immotile spermatozoa or severe male factors.

The system is aligned with the latest ESHRE guidelines, which recognize electroporation (piezoelectric activation) as one of the few recommended "add-on" technologies in IVF. Unlike chemical methods, our device is designed to mimic physiological calcium spikes, providing a safer and more effective alternative for oocyte activation.

In physiological fertilization, the sperm triggers calcium oscillations within the oocyte to initiate development. In cases such as Round Spermatid Injection (ROSI) or severe male factor infertility, the sperm may lack the necessary factors (like PLCζ) to trigger this activation. AOA is clinically indicated in these instances to mimic the natural fertilization process and prevent fertilization failure.

These oscillations more closely mimic natural fertilization rhythms, which are critical for embryo development and quality. Unlike traditional chemical ionophores, which may involve toxicity risks and longer incubation times, the ZEUS Pulse Stimulator delivers a stable, standardized pulse that induces physiological-like calcium oscillations within seconds. This non-toxic method more closely replicates natural fertilization compared to monophasic chemical activation.

Yes, the system offers two distinct clinical protocols: DC Mode (standard 70 µs pulse typically used pre/post-ICSI) and AC/DC Mode (5-second cell alignment followed by a 70 µs pulse, designed for ROSI purposes).

Yes. Clinical reality and follow-up studies, including those for ROSI, show that physical and cognitive development at two years of age is comparable to children born via standard ICSI. With over 90 healthy live births reported through these specialized methods, the ZEUS Pulse Stimulator remains a safe and reliable option for patients with Non-obstructive Azoospermia (NOA).

The ZEUS Mismatch Blocker is a witnessing system designed to secure the Gamete–Embryo–Patient triangle. Unlike expensive chip-based technologies that rely on high per-procedure costs, our system utilizes QR codes to provide a low-cost, high-security solution for the entire IVF process. While the system offers unlimited and free barcode usage, it operates on a coin-based model per cycle. This allows clinics to maintain a cost-predictable model by purchasing credits (coins) via a virtual POS, which are credited instantly to the account for immediate use. This approach ensures complete end-to-end traceability without the burden of expensive, recurring consumable fees.

It features an Intelligent Warning System that triggers an immediate, high-visibility alert if a barcode from a different patient is scanned, preventing any cross-contamination

The system uses mobile, wireless touchscreen terminals integrated with barcode readers, eliminating contamination risks from cables on laminar surfaces. In addition, Physicians and even patients can access embryo development information 24/7 through a dedicated smartphone application.

Providing complete witnessing at every stage and in every location, from the OPU room to the nitrogen tank. 1 × Sperm Collection Room 1 × Andrology Room1 × OPU Entrance1 × OPU Room (in front of the physician)1 × Embryology Laboratory (laminar flow cabinet)1 × Micromanipulator Desk1 × Freezing Room

Verification begins with a keyboard-free login where spouses scan their identity cards. Patients receive barcoded bracelets verified at every touchpoint. An "Active Patient Lock" ensures that only the patient currently being treated is active on the terminal screen to prevent cross-contamination of data.